Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming
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DOI: 10.1126/sciadv.aay1109
Abstract: Protein modification with ISG15 acts cooperatively with IFIT proteins and preserves glucose homeostasis. Protein modification with ISG15 (ISGylation) represents a major type I IFN–induced antimicrobial system. Common mechanisms of action and species-specific aspects of ISGylation,… read more here.
Keywords: modification isg15; protein modification; isgylation; pathology ... See more keywords