Imaging Glycosaminoglycan Modification Patterns In Vivo.
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DOI: 10.1007/978-1-0716-1398-6_42
Abstract: Glycosaminoglycans (GAGs) such as heparan sulfates (HS) or chondroitin sulfates (CS) are long unbranched polymers of a disaccharide comprised of hexuronic acid and hexosamine. Attached to a protein backbone via a characteristic tetrasaccharide, the GAG… read more here.
Keywords: patterns vivo; modification patterns; gag; glycosaminoglycan modification ... See more keywords
RNA modification “writer”-mediated RNA modification patterns and tumor microenvironment characteristics of cervical cancer
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DOI: 10.1007/s12094-022-02787-x
Abstract: As an epigenetic regulation mechanism after transcription, RNA modification is installed by endogenous "writer" enzymes and is widely involved in a variety of physiological processes, including cancer progression. This study explored the RNA modification patterns… read more here.
Keywords: cervical cancer; modification; rna modification; modification patterns ... See more keywords
m6A regulator‐mediated RNA methylation modification patterns are involved in immune microenvironment regulation of periodontitis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16469
Abstract: The role of epigenetic regulation in immunity is emerging, especially for RNA N6‐methyladenosine (m6A) modification. However, little is known about the role of m6A in the regulation of the immune microenvironment of periodontitis. Thus, we… read more here.
Keywords: modification patterns; immune microenvironment; m6a; modification ... See more keywords
Characterization of m6A Methylation Modification Patterns in Colorectal Cancer Determines Prognosis and Tumor Microenvironment Infiltration
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DOI: 10.1155/2022/8766735
Abstract: Cumulative studies have suggested that dysregulation of m6A regulators and immunity is highly linked to the prognosis of patients with cancer. However, the potential contribution of m6A modification patterns to the tumor microenvironment (TME) and… read more here.
Keywords: modification; m6a modification; m6a methylation; m6a ... See more keywords
m1A methylation modification patterns and metabolic characteristics in hepatocellular carcinoma
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DOI: 10.1186/s12876-022-02160-w
Abstract: Background The dysregulation of RNA methylation has been demonstrated to contribute to tumorigenicity and progression in recent years. However, the alteration of N1-methyladenosine (m1A) methylation and its role in hepatocellular carcinoma (HCC) remain unclear. Methods… read more here.
Keywords: modification patterns; m1a methylation; metabolic characteristics; modification ... See more keywords
M5C regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in lung adenocarcinoma.
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DOI: 10.21037/tlcr-21-351
Abstract: Background In recent years, immunotherapy has made great progress, and the regulatory role of epigenetics has been verified. However, the role of 5-methylcytosine (m5C) in the tumor microenvironment (TME) and immunotherapy response remains unclear. Methods… read more here.
Keywords: infiltration; modification patterns; m5c; tumor microenvironment ... See more keywords
m6A Regulator-Mediated Methylation Modification Patterns and Characterisation of Tumour Microenvironment Infiltration in Non-Small Cell Lung Cancer
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DOI: 10.2147/jir.s356841
Abstract: Purpose The role of RNA N6-methyladenosine (m6A) modification in the progression of multiple tumours and the tumour microenvironment (TME) has been progressively demonstrated and promises a new direction for tumour therapy. However, there have been… read more here.
Keywords: tumour microenvironment; modification; m6a modification; m6a ... See more keywords
Characterization of m6A Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration in Ovarian Cancer
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DOI: 10.3389/fcell.2021.794801
Abstract: Introduction: Studies have demonstrated the epigenetic regulation of immune responses in various cancers. However, little is known about the RNA N6-methyladenosine (m6A) modification patterns of the microenvironment (TME) cell infiltration in ovarian cancer (OC). Methods:… read more here.
Keywords: infiltration; modification; m6a modification; tme cell ... See more keywords
Analysis of m6A Methylation Modification Patterns and Tumor Immune Microenvironment in Breast Cancer
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DOI: 10.3389/fcell.2022.785058
Abstract: Increasing evidence indicates that the abnormal expression of N6-methyladenosine (m6A) modification is closely related to the epigenetic regulation of immune response in breast cancer (BC). However, the potential roles of m6A modification in the tumor… read more here.
Keywords: modification; m6a modification; analysis; m6a ... See more keywords
Identification of New m6A Methylation Modification Patterns and Tumor Microenvironment Infiltration Landscape that Predict Clinical Outcomes for Papillary Renal Cell Carcinoma Patients
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DOI: 10.3389/fcell.2022.818194
Abstract: N6-methyladenosine (m6A) is the product of the most prevalent mRNA modification in eukaryotic cells. Accumulating evidence shows that tumor microenvironment (TME) plays a pivotal role in tumor development. However, the underlying relationship between m6A modification… read more here.
Keywords: modification; m6a modification; cell; tumor microenvironment ... See more keywords
Glycosylation modification patterns reveal distinct tumor metabolism and immune microenvironment landscape in lower-grade gliomas
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DOI: 10.3389/fcell.2022.886989
Abstract: Glycosylation alterations, a key driver throughout tumorigenesis and tumor progression, could regulate the microenvironment and immune response as well as lead to harmful metabolism and cell signaling. In this study, we first comprehensively evaluated the… read more here.
Keywords: modification; metabolism immune; glycosylation modification; glycosylation ... See more keywords