DNA methylation by three Type I restriction modification systems of Escherichia coli does not influence gene regulation of the host bacterium
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DOI: 10.1093/nar/gkab530
Abstract: Abstract DNA methylation is a common epigenetic mark that influences transcriptional regulation, and therefore cellular phenotype, across all domains of life. In particular, both orphan methyltransferases and those from phasevariable restriction modification systems (RMSs) have… read more here.
Keywords: methylation; restriction modification; modification systems; type ... See more keywords
A model for the evolution of prokaryotic DNA restriction-modification systems based upon the structural malleability of Type I restriction-modification enzymes
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DOI: 10.1093/nar/gky760
Abstract: Abstract Restriction Modification (RM) systems prevent the invasion of foreign genetic material into bacterial cells by restriction and protect the host's genetic material by methylation. They are therefore important in maintaining the integrity of the… read more here.
Keywords: restriction; restriction modification; modification systems; type ... See more keywords
DNA Methylation by Restriction Modification Systems Affects the Global Transcriptome Profile in Borrelia burgdorferi
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DOI: 10.1128/jb.00395-18
Abstract: Lyme disease is the most prevalent vector-borne disease in North America and is classified by the Centers for Disease Control and Prevention (CDC) as an emerging infectious disease with an expanding geographical area of occurrence.… read more here.
Keywords: methylation; restriction modification; modification systems; gene ... See more keywords