Quantification of mRNA cap-modifications by means of LC-QqQ-MS.
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DOI: 10.1016/j.ymeth.2021.05.018
Abstract: Enzymatic modification of the 5'-cap is a versatile approach to modulate the properties of mRNAs. Transfer of methyl groups from S-adenosyl-L-methionine (AdoMet) or functional moieties from non-natural analogs by methyltransferases (MTases) allows for site-specific modifications… read more here.
Keywords: mrna cap; modifications means; cap modifications; quantification mrna ... See more keywords