Accurate detection of m6A RNA modifications in native RNA sequences
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-11713-9
Abstract: The epitranscriptomics field has undergone an enormous expansion in the last few years; however, a major limitation is the lack of generic methods to map RNA modifications transcriptome-wide. Here, we show that using direct RNA… read more here.
Keywords: modifications native; rna; rna modifications; m6a rna ... See more keywords
Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.871937
Abstract: Bacterial DNA is subject to various modifications involved in gene regulation and defense against bacteriophage attacks. Phosphorothioate (PT) modifications are protective modifications in which the non-bridging oxygen in the DNA phosphate backbone is replaced with… read more here.
Keywords: phosphorothioate modifications; dna; detection; modifications native ... See more keywords