Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis
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DOI: 10.1172/jci.insight.146196
Abstract: Development of primary liver cancer is a multistage process. Detailed understanding of sequential epigenetic alterations is largely missing. Here, we performed Infinium Human Methylation 450k BeadChips and RNA-Seq analyses for genome-wide methylome and transcriptome profiling… read more here.
Keywords: epigenetic modifications; precede molecular; modifications precede; alterations drive ... See more keywords