Incorporation of Modified Amino Acids by Engineered Elongation Factors with Expanded Substrate Capabilities
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DOI: 10.1021/acssynbio.8b00305
Abstract: Noncanonical amino acid (ncAA) incorporation has led to significant advances in protein science and engineering. Traditionally, in vivo incorporation of ncAAs is achieved via amber codon suppression using an engineered orthogonal aminoacyl-tRNA synthetase:tRNA pair. However,… read more here.
Keywords: modified amino; incorporation modified; amino acids; elongation ... See more keywords
Crystal structures of N6-modified-amino acid related nucleobase analogs (II): hybrid adenine-β-alanine and adenine-GABA molecules
Sign Up to like & getrecommendations! Published in 2019 at "New Journal of Chemistry"
DOI: 10.1039/c9nj02279a
Abstract: H-Bonding networks and anion–π interactions in the crystal structures of N6-modified-amino acid adenine analogs are investigated using X-ray crystallography and DFT calculations. read more here.
Keywords: crystal structures; modified amino; structures modified; adenine ... See more keywords