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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0876-0_12
Abstract: DNA methylation undergoes dynamic changes at the genome-wide scale during the early steps of mammalian embryo development. Immunochemical detection of 5-methylcytosine (5mC) in the zygote has led to the discovery that a global loss of…
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Keywords:
cytosine species;
dna;
preimplantation embryos;
immunochemical detection ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0876-0_13
Abstract: The lampbrush chromosomes found in the giant nucleus or germinal vesicle (GV) of amphibian oocytes provide unique opportunities for discrete closed and open chromatin structural domains to be directly observable by simple light microscopy. Moreover,…
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Keywords:
cytosine species;
chromatin;
immunochemical detection;
modified cytosine ... See more keywords