NHC-Catalyzed [3 + 3] Annulation of Thioamides and Modified Enals for the Enantioselective Synthesis of Functionalized Thiazinones.
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DOI: 10.1021/acs.orglett.9b03188
Abstract: N-Heterocyclic carbene (NHC)-catalyzed [3 + 3] annulation of thioamides with modified enals allowing the enantioselective synthesis of functionalized 1,3-thiazin-4-ones is reported. The NHC generated from the chiral triazolium salt was optimal and the reaction is… read more here.
Keywords: nhc catalyzed; annulation thioamides; modified enals; thioamides modified ... See more keywords