Total Synthesis and Biological Evaluation of Modified Ilamycin Derivatives
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DOI: 10.3390/md20100632
Abstract: Ilamycins/rufomycins are marine cycloheptapeptides containing unusual amino acids. Produced by Streptomyces sp., these compounds show potent activity against a range of mycobacteria, including multidrug-resistant strains of Mycobacterium tuberculosis. The cyclic peptides target the AAA+ protein… read more here.
Keywords: synthesis biological; ilamycin derivatives; biological evaluation; modified ilamycin ... See more keywords