Hyaluronic-acid-modified lipid-polymer hybrid nanoparticles as an efficient ocular delivery platform for moxifloxacin hydrochloride.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.05.113
Abstract: To improve the ocular bioavailability of the strongly hydrophilic moxifloxacin hydrochloride, hyaluronic-acid-modified lipid-polymer hybrid nanoparticles (HA-LCS-NPs) were designed and characterized. An in vivo precorneal retention study in rabbits showed that the mean residence time (MRT)… read more here.
Keywords: lcs nps; lipid polymer; modified lipid; hyaluronic acid ... See more keywords
Size-optimized simvastatin TPGS modified lipid nanocapsules for targeting epithelial-to-mesenchymal transition in hepatocellular carcinoma: role of PTEN/AKT signaling.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on drug delivery"
DOI: 10.1080/17425247.2023.2216451
Abstract: OBJECTIVES Novel D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) modified lipid nanocapsules (LNC) were prepared with the aim of improving the effectiveness of simvastatin (SIM) in hepatocellular carcinoma (HCC). The present study, therefore, sought to investigate… read more here.
Keywords: pten akt; tpgs modified; sim; modified lipid ... See more keywords