Development of a broadly protective modified-live virus vaccine candidate against porcine reproductive and respiratory syndrome virus.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.11.028
Abstract: Modified-live virus (MLV) vaccines are widely used to protect pigs against porcine reproductive and respiratory syndrome virus (PRRSV). However, current MLV vaccines do not confer adequate levels of heterologous protection, presumably due to the substantial… read more here.
Keywords: con; modified live; vaccine; virus ... See more keywords
A Conserved Stem-Loop Structure within ORF5 Is a Frequent Recombination Hotspot for Porcine Reproductive and Respiratory Syndrome Virus 1 (PRRSV-1) with a Particular Modified Live Virus (MLV) Strain
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15010258
Abstract: The emergence of recombinant PRRSV strains has been observed for more than a decade. These recombinant viruses are characterized by a genome that contains genetic material from at least two different parental strains. Due to… read more here.
Keywords: modified live; prrsv; stem loop; recombination ... See more keywords
Phenotypic and Genetic Evolutions of a Porcine Reproductive and Respiratory Syndrome Modified Live Vaccine after Limited Passages in Pigs
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DOI: 10.3390/vaccines9040392
Abstract: Modified live vaccines (MLVs) against the porcine reproductive and respiratory syndrome virus (PRRSV) have been regularly associated with safety issues, such as reversion to virulence. In order to characterize the phenotypic and genetic evolution of… read more here.
Keywords: trial; passages pigs; limited passages; modified live ... See more keywords
Impacts of Quarterly Sow Mass Vaccination with a Porcine Reproductive and Respiratory Syndrome Virus Type 1 (PRRSV-1) Modified Live Vaccine in Two Herds
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DOI: 10.3390/vaccines9101057
Abstract: In recent years, there has been a considerable increase in the use of Modified Live PRRSV Vaccines (MLV) for mass vaccination in Denmark. The potential risks and negative impact of this strategy have been sparsely… read more here.
Keywords: mass vaccination; modified live; vaccination; virus ... See more keywords
PRRSV Detection by qPCR on Serum Samples Collected in Due-to-Wean Piglets in Five Positive Stable Breeding Herds Following a Sow Mass Vaccination with a Modified Live Vaccine: A Descriptive Study
Sign Up to like & getrecommendations! Published in 2023 at "Veterinary Sciences"
DOI: 10.3390/vetsci10040294
Abstract: Simple Summary The purpose of this study was to describe vaccinal strain detection using qPCR on blood samples collected from due-to-wean piglets after a mass vaccination of their dams with a modified live vaccine in… read more here.
Keywords: modified live; vaccination; study; vaccine ... See more keywords
Evaluation of Intrathecal Injection of Modified Live Newcastle Disease Virus Vaccine in Dogs with Canine Distemper Encephalitis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Animal Hospital Association"
DOI: 10.5326/jaaha-ms-7077
Abstract: The neurological form of canine distemper virus (CDV) infection can occur concurrently with systemic signs or develop following apparent recovery. There are no specific antiviral or immunomodulatory therapies recognized for treatment of CDV infections, and… read more here.
Keywords: injection; modified live; intrathecal injection; injection modified ... See more keywords