Synthesis and Evaluations of Cleavable Triazene‐Modified Nucleotide for DNA Sequencing
Sign Up to like & getrecommendations! Published in 2024 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202400393
Abstract: A fluorescence‐labeled nucleotide with a cleavable triazene linker was designed and synthesized as a potential reversible terminator for DNA sequencing by synthesis (SBS). The key intermediate, a triazene‐modified nucleotide, was successfully synthesized through the triazenylation… read more here.
Keywords: cleavable triazene; dna sequencing; modified nucleotide; triazene modified ... See more keywords
Chemical-Modified Nucleotide-Based Elemental Tags for High-Sensitive Immunoassay.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00405
Abstract: Multiplex biomolecular analysis with inductively coupled plasma mass spectrometry (ICP-MS) becomes increasingly important in clinical diagnosis and single cell analysis. However, the sensitivity of ICP-MS-based immunoassay is only comparable or lower than those of fluorescence… read more here.
Keywords: elemental tags; chemical modified; high sensitive; modified nucleotide ... See more keywords