Synthesis of N2‐Aryl‐2′‐Deoxyguanosine Modified Phosphoramidites and Oligonucleotides
Sign Up to like & getrecommendations! Published in 2019 at "Current Protocols in Nucleic Acid Chemistry"
DOI: 10.1002/cpnc.93
Abstract: The N2‐position of 2′‐deoxyguanosine (N2‐position in dG) is well known for forming carcinogenic minor groove DNA adducts, which originate from environmental pollutants, chemicals, and tobacco smoke. The N2‐dG DNA adducts have strong implications on biological… read more here.
Keywords: modified phosphoramidites; dna; synthesis; deoxyguanosine ... See more keywords