Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary Immunology and Immunopathology"
DOI: 10.1016/j.vetimm.2017.01.004
Abstract: Abstract A reverse vaccinology system, Vaxign, was used to identify and select a subset of five African Swine Fever (ASF) antigens that were successfully purified from human embryonic kidney 293 (HEK) cells and produced in… read more here.
Keywords: swine fever; african swine; modified vaccinia; safety immunogenicity ... See more keywords
Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans
Sign Up to like & getrecommendations! Published in 2020 at "NPJ Vaccines"
DOI: 10.1038/s41541-020-00240-0
Abstract: Simian adenoviral and modified vaccinia Ankara (MVA) viral vectors used in heterologous prime-boost strategies are potent inducers of T cells against encoded antigens and are in advanced testing as vaccine carriers for a wide range… read more here.
Keywords: mva nsmut; modified vaccinia; vaccinia ankara; mva ... See more keywords
Immunogenicity of modified vaccinia virus Ankara expressing the hemagglutinin stalk domain of pandemic (H1N1) 2009 influenza virus
Sign Up to like & getrecommendations! Published in 2017 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2016.1275464
Abstract: Abstract Background: Vaccination offers protection against influenza, although current vaccines need to be reformulated each year. The development of a broadly protective influenza vaccine would guarantee the induction of heterosubtypic immunity also against emerging influenza… read more here.
Keywords: modified vaccinia; influenza; vaccinia virus; virus ankara ... See more keywords
Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers
Sign Up to like & getrecommendations! Published in 2017 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2016.0251
Abstract: Abstract We explored the duration of immune responses and the effect of a late third HIV-modified vaccinia virus Ankara (MVA) boost in HIV-DNA primed and HIV-MVA boosted Tanzanian volunteers. Twenty volunteers who had previously received… read more here.
Keywords: modified vaccinia; hiv; vaccinia virus; virus ankara ... See more keywords
Induction of Both Local Immune Response in Mice and Protection in a Rabbit Model by Intranasal Immunization with Modified Vaccinia Ankara Virus Expressing a Secreted Form of Bovine Herpesvirus 1 Glycoprotein D.
Sign Up to like & getrecommendations! Published in 2017 at "Viral immunology"
DOI: 10.1089/vim.2016.0090
Abstract: In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D (MVA-gDs) without addition… read more here.
Keywords: immune; ankara virus; modified vaccinia; vaccinia ankara ... See more keywords
Clinical characteristics of mpox infection in individuals who received a first dose of modified vaccinia Ankara immunisation
Sign Up to like & getrecommendations! Published in 2023 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2022-055698
Abstract: Introduction A key part of the response to the mpox (monkeypox) epidemic has been the vaccination campaign targeted at gay, bisexual and other men who have sex with men (GBM), including people living with HIV… read more here.
Keywords: individuals received; vaccinia ankara; modified vaccinia; first dose ... See more keywords
Modified vaccinia Ankara expressing EEHV1A glycoprotein B elicits humoral and cell-mediated immune responses in mice
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0265424
Abstract: Elephant endotheliotropic herpesvirus (EEHV) can cause lethal hemorrhagic disease (EEHV-HD) in Asian elephants and is the largest cause of death in captive juvenile Asian elephants in North America and Europe. EEHV-HD also has been documented… read more here.
Keywords: cell; vaccinia ankara; modified vaccinia; humoral cell ... See more keywords
Outcomes of post-exposure vaccination by modified vaccinia Ankara to prevent mpox (formerly monkeypox): a retrospective observational study in Lyon, France, June to August 2022
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DOI: 10.2807/1560-7917.es.2022.27.50.2200882
Abstract: Modified vaccinia virus Ankara vaccine (MVA-BN; Bavarian Nordic) is recommended to contacts of mpox cases up to 14 days post-exposure but the effectiveness of this strategy is unknown. Among 108 adults (≥ 18 years old) who received one… read more here.
Keywords: ankara; modified vaccinia; mpox cases; exposure ... See more keywords
Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine
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DOI: 10.3389/fimmu.2018.00870
Abstract: New vaccine design approaches would be greatly facilitated by a better understanding of the early systemic changes, and those that occur at the site of injection, responsible for the installation of a durable and oriented… read more here.
Keywords: response; ankara; modified vaccinia; injection ... See more keywords
A Single Dose of Modified Vaccinia Ankara Expressing Lassa Virus-like Particles Protects Mice from Lethal Intra-cerebral Virus Challenge
Sign Up to like & getrecommendations! Published in 2019 at "Pathogens"
DOI: 10.3390/pathogens8030133
Abstract: Lassa fever surpasses Ebola, Marburg, and all other hemorrhagic fevers except Dengue in its public health impact. Caused by Lassa virus (LASV), the disease is a scourge on populations in endemic areas of West Africa,… read more here.
Keywords: challenge; modified vaccinia; vaccinia ankara; geo lm01 ... See more keywords
Protective CD8+ T Cell Response Induced by Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10040533
Abstract: The urgent need for vaccines against Ebola virus (EBOV) was underscored by the large outbreak in West Africa (2014–2016). Since then, several promising vaccine candidates have been tested in pre-clinical and clinical studies. As a… read more here.
Keywords: mva ebov; modified vaccinia; ebola virus; virus ... See more keywords