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Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-30651-9_13
Abstract: Signal transduction pathways directly communicate and transform chromatin to change the epigenetic landscape and regulate gene expression. Chromatin acts as a dynamic platform of signal integration and storage. Histone modifications and alteration of chromatin structure…
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Keywords:
enzymes chromatin;
histone modifying;
chromatin modifiers;
modifying enzymes ... See more keywords
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Published in 2019 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2019.08.026
Abstract: OBJECTIVE Carbapenemase producingEnterobacterales are often involved in healthcare-associated infections worldwide. Therefore, the objective of this study was to investigate the frequency of the main genes for carbapenemases, methylases, aminoglycoside-modifying enzymes (AMEs), and mcr gene, as…
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Keywords:
blandm blakpc;
modifying enzymes;
aminoglycoside modifying;
mirabilis ... See more keywords
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Published in 2018 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2018.01.007
Abstract: Background To maintain homeostasis, cells need to coordinate the expression of their genes. Epigenetic mechanisms controlling transcription activation and repression include DNA methylation and post-translational modifications of histones, which can affect the architecture of chromatin…
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Keywords:
intermediates cellular;
chromatin;
metabolic intermediates;
modifying enzymes ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.1101/2022.01.07.475340
Abstract: Antibiotics consumption and its abuses have been historically and repeatedly pointed out as the major driver of antibiotic resistance emergence and propagation. However, several examples show that resistance may persist despite substantial reductions in antibiotic…
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Keywords:
antibiotics consumption;
ecology;
consumption;
modifying enzymes ... See more keywords
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Published in 2018 at "Biotechnology for Biofuels"
DOI: 10.1186/s13068-018-1261-2
Abstract: BackgroundProducing valuable fuels and chemicals from lignin is a key factor for making lignocellulosic biomass economically feasible; however, significant roadblocks exist due to our lack of detailed understanding of how lignin is enzymatically depolymerized and…
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Keywords:
carbon;
modifying enzymes;
lignin modifying;
reaction ... See more keywords
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Published in 2021 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0599-2020
Abstract: Abstract INTRODUCTION: This study aimed to determine the role of genes encoding aminoglycoside-modifying enzymes (AMEs) and 16S rRNA methylase (ArmA) in Acinetobacter baumannii clinical isolates. METHODS: We collected 100 clinical isolates of A. baumannii and…
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Keywords:
modifying enzymes;
arma;
16s rrna;
aminoglycoside modifying ... See more keywords
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Published in 2021 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s290584
Abstract: Background Acinetobacter baumannii is an opportunistic pathogen that rapidly develops antibiotic resistance against commonly prescribed antimicrobial agents in hospitalized patients worldwide. Aminoglycosides are commonly used in the treatment of A. baumannii health care-associated infections (HAIs).…
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Keywords:
care;
baumannii;
modifying enzymes;
resistance ... See more keywords
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Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1107323
Abstract: Huntington’s disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the N-terminus of the HTT gene. The CAG repeat expansion translates into a polyglutamine expansion in the mutant HTT (mHTT) protein,…
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Keywords:
huntington disease;
ubiquitin modifying;
modifying enzymes;
expansion ... See more keywords
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Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11070884
Abstract: Aminoglycosides are widely used to treat infections of Pseudomonas aeruginosa. Genes encoding aminoglycoside-modifying enzymes (AMEs), acquired by horizontal gene transfer, are commonly associated with aminoglycoside resistance, but their effects have not been quantified. The aim…
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Keywords:
pseudomonas aeruginosa;
aminoglycoside modifying;
resistance;
modifying enzymes ... See more keywords
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Published in 2018 at "Cancers"
DOI: 10.3390/cancers11010006
Abstract: It is well established that cancer cells exhibit alterations in chromatin structure and accessibility. Indeed, the dysregulation of many protein-coding players with enzymatic activity (DNA and histone-modifying enzymes) and chromatin remodelers have been depicted in…
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Keywords:
enzymes chromatin;
dna;
histone modifying;
modifying enzymes ... See more keywords
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Published in 2021 at "Cancers"
DOI: 10.3390/cancers14010006
Abstract: Simple Summary Microtubules are tubulin polymers that constitute the structure of eukaryotic cells. They control different cell functions that are often deregulated in cancer, such as cell shape, cell motility and the intracellular movement of…
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Keywords:
cancer;
tubulin;
tubulin code;
cell ... See more keywords