Domain Expansion and Functional Diversification in Vertebrate Reproductive Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1101/2022.01.31.478407
Abstract: The rapid evolution of fertilization proteins can result in remarkable diversity in their structure and function. Many of the proteins in vertebrate egg coats contain copies (1-6) of the ZP-N domain. These ZP-N domains can… read more here.
Keywords: modular domains; expansion functional; free domains; domain expansion ... See more keywords
The PRR14 heterochromatin tether encodes modular domains that mediate and regulate nuclear lamina targeting
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.240416
Abstract: ABSTRACT A large fraction of epigenetically silent heterochromatin is anchored to the nuclear periphery via ‘tethering proteins’ that function to bridge heterochromatin and the nuclear membrane or nuclear lamina. We previously identified a human tethering… read more here.
Keywords: heterochromatin; nuclear lamina; modular domains; prr14 ... See more keywords