An integrated modular framework for modeling the effect of ammonium on the sialylation process of monoclonal antibodies produced by CHO cells
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Journal"
DOI: 10.1002/biot.202100019
Abstract: Monoclonal antibodies (mABs) have emerged as one of the most important therapeutic recombinant proteins in the pharmaceutical industry. Their immunogenicity and therapeutic efficacy are influenced by post‐translational modifications, specifically the glycosylation process. Bioprocess conditions can… read more here.
Keywords: integrated modular; modular framework; monoclonal antibodies; process ... See more keywords
The compatibility within a modular framework of emergent and dynamical processes in mind and brain
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurolinguistics"
DOI: 10.1016/j.jneuroling.2018.04.010
Abstract: Abstract In the light of the continuing controversy over evidence supporting emergentist and non-emergentist accounts of cognitive and brain development, this commentary compares the proposals for a neuroemergentist framework for studying cognition and the brain… read more here.
Keywords: modular framework; framework; compatibility within; mind brain ... See more keywords
TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms
Sign Up to like & getrecommendations! Published in 2018 at "BMC Bioinformatics"
DOI: 10.1186/s12859-018-2384-y
Abstract: BackgroundThe advances in high-throughput sequencing technologies are allowing more and more de novo assembling of transcriptomes from many new organisms. Some degree of automation and evaluation is required to warrant reproducibility, repetitivity and the selection… read more here.
Keywords: novo transcriptomes; roche 454; modular framework; evaluation ... See more keywords