Modular peptide-functionalized gold nanorods for effective glioblastoma multicellular tumor spheroid targeting.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c7bm01107e
Abstract: Glioblastoma multiforme (GBM) contains a population of tumor initiating stem-like cells, termed cancer stem cells (CSCs). These CSCs, which are resistant to chemo- and radiotherapy, are thought to persist after treatment and drive tumor recurrence.… read more here.
Keywords: glioblastoma; modular peptide; gbm; multicellular tumor ... See more keywords
Abstract 2929: Modular peptide cargo delivery by targeting CD40 enables ligandome driven, precision immunotherapy via the Adaptable Drug Affinity Conjugate (ADAC™) technology
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2929
Abstract: Agonistic anti-CD40 therapy has shown impressive efficacy in preclinical murine models, models inert to toxicity of high systemic drug exposure. Clinical data consist of pharmacodynamic responses reported as non-specific cytokine release, transient drop of CD40-expressing… read more here.
Keywords: modular peptide; cd40; drug; delivery ... See more keywords
Modular peptide binders – development of a predictive technology as alternative for reagent antibodies
Sign Up to like & getrecommendations! Published in 2022 at "Biological Chemistry"
DOI: 10.1515/hsz-2021-0384
Abstract: Abstract Current biomedical research and diagnostics critically depend on detection agents for specific recognition and quantification of protein molecules. Monoclonal antibodies have been used for this purpose over decades and facilitated numerous biological and biomedical… read more here.
Keywords: binders development; reagent; modular peptide; reagent antibodies ... See more keywords