Mitochondrial-nuclear cross-talk in the human brain is modulated by cell type and perturbed in neurodegenerative disease
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DOI: 10.1038/s42003-021-02792-w
Abstract: Mitochondrial dysfunction contributes to the pathogenesis of many neurodegenerative diseases. The mitochondrial genome encodes core respiratory chain proteins, but the vast majority of mitochondrial proteins are nuclear-encoded, making interactions between the two genomes vital for… read more here.
Keywords: modulated cell; human brain; disease; mitochondrial nuclear ... See more keywords