TREM2 modulates microglia phenotypes in the neuroinflammation of Parkinson's disease.
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DOI: 10.1016/j.bbrc.2018.03.226
Abstract: Neuroinflammation and overactivated microglia underlies the pathogenesis of Parkinson's disease (PD). Furthermore, microglia could polarize into classic inflammatory M1 and immunosuppressive M2 phenotype. Thus, inhibiting the overactivated inflammatory M1 microglia by promoting the transformation of… read more here.
Keywords: trem2; neuroinflammation; modulates microglia; polarization ... See more keywords