The serotonin reuptake transporter modulates mitochondrial copy number and mitochondrial respiratory complex gene expression in the frontal cortex and cerebellum in a sexually dimorphic manner
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25010
Abstract: Neuropsychiatric and neurodevelopmental disorders such as major depressive disorder (MDD) and autism spectrum disorder (ASD) are complex conditions attributed to both genetic and environmental factors. There is a growing body of evidence showing that serotonergic… read more here.
Keywords: reduced sert; modulates mitochondrial; transporter; sert expression ... See more keywords
DJ‐1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genetics"
DOI: 10.1111/cge.12841
Abstract: DJ‐1 mutations are associated to early‐onset Parkinson's disease and accounts for about 1–2% of the genetic forms. The protein is involved in many biological processes and its role in mitochondrial regulation is gaining great interest,… read more here.
Keywords: response oxidative; mitochondrial response; modulates mitochondrial; stress ... See more keywords
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Reports"
DOI: 10.15252/embr.202052006
Abstract: Abstract Tunneling nanotubes (TNTs) are actin‐rich structures that connect two or more cells and mediate cargo exchange between spatially separated cells. TNTs transport signaling molecules, vesicles, organelles, and even pathogens. However, the molecular mechanisms regulating… read more here.
Keywords: tunneling nanotubes; mitochondrial trafficking; modulates mitochondrial; mical2pv ... See more keywords
Viral Infection Modulates Mitochondrial Function
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DOI: 10.3390/ijms22084260
Abstract: Mitochondria are important organelles involved in metabolism and programmed cell death in eukaryotic cells. In addition, mitochondria are also closely related to the innate immunity of host cells against viruses. The abnormality of mitochondrial morphology… read more here.
Keywords: infection modulates; modulates mitochondrial; viral infection; host ... See more keywords
cAMP/PKA Signaling Modulates Mitochondrial Supercomplex Organization
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DOI: 10.3390/ijms23179655
Abstract: The oxidative phosphorylation (OXPHOS) system couples the transfer of electrons to oxygen with pumping of protons across the inner mitochondrial membrane, ensuring the ATP production. Evidence suggests that respiratory chain complexes may also assemble into… read more here.
Keywords: modulates mitochondrial; pka signaling; production; signaling modulates ... See more keywords