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Published in 2017 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00264-17
Abstract: ABSTRACT Loss-of-function mutations in 3′-to-5′ exoribonucleases have been implicated in hereditary human diseases. For example, PARN mutations cause a severe form of dyskeratosis congenita (DC), wherein PARN deficiency leads to human telomerase RNA instability. Since…
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Keywords:
parn modulates;
end;
modulates rna;
rna stability ... See more keywords