Modulating autophagic flux via ROS-responsive targeted micelles to restore neuronal proteostasis in Alzheimer's disease
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DOI: 10.1016/j.bioactmat.2021.09.017
Abstract: Abstract Compromised autophagy and defective lysosomal clearance significantly contribute to impaired neuronal proteostasis, which represents a hallmark of Alzheimer's disease (AD) and other age-related neurodegenerative disorders. Growing evidence has implicated that modulating autophagic flux, instead… read more here.
Keywords: modulating autophagic; alzheimer disease; autophagic flux; neuronal proteostasis ... See more keywords