Agomelatine attenuates alcohol craving and withdrawal symptoms by modulating the Notch1 signaling pathway in rats.
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DOI: 10.1016/j.lfs.2021.119904
Abstract: AIM Alcohol abuse is a significant causative factor of death worldwide. The Notch1 signaling pathway is involved in alcohol tolerance, withdrawal and dependence. Agomelatine is a known antidepressant acting as a melatonin receptor (MT1/2) agonist… read more here.
Keywords: notch1 signaling; signaling pathway; modulating notch1; withdrawal symptoms ... See more keywords