Modulation of Amyloid-β42 Conformation by Small Molecules Through Non-Specific Binding.
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DOI: 10.1021/acs.jctc.9b00599
Abstract: Aggregation of amyloid-β (Aβ) peptides is a crucial step in the progression of Alzheimer's disease (AD). Identifying aggregation inhibitors against AD has been a great challenge. We report an atomistic simulation study of the inhibition… read more here.
Keywords: specific binding; amyloid conformation; non specific; small molecules ... See more keywords