Modulation of Cancer Metabolism by Phytochemicals - A Brief Overview.
Sign Up to like & getrecommendations! Published in 2018 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520617666171114102218
Abstract: Despite tremendous research efforts for effective therapies, cancer remains the plague of the century and its burden is expected to increase worldwide in the near future. Metabolic reprogramming is a firmly established hallmark of all… read more here.
Keywords: modulation cancer; metabolism; metabolism phytochemicals; cancer metabolism ... See more keywords
VDAC Modulation of Cancer Metabolism: Advances and Therapeutic Challenges
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.742839
Abstract: Most anionic metabolites including respiratory substrates, glycolytic adenosine triphosphate (ATP), and small cations that enter mitochondria, and mitochondrial ATP moving to the cytosol, cross the outer mitochondrial membrane (OMM) through voltage dependent anion channels (VDAC).… read more here.
Keywords: modulation cancer; vdac modulation; metabolism; mitochondrial metabolism ... See more keywords
Phenotypic Modulation of Cancer-Associated Antioxidant NQO1 Activity by Post-Translational Modifications and the Natural Diversity of the Human Genome
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020379
Abstract: Human NAD(P)H:quinone oxidoreductase 1 (hNQO1) is a multifunctional and antioxidant stress protein whose expression is controlled by the Nrf2 signaling pathway. hNQO1 dysregulation is associated with cancer and neurological disorders. Recent works have shown that… read more here.
Keywords: translational modifications; modulation cancer; post translational; phenotypic modulation ... See more keywords
The Landscape of Nanovectors for Modulation in Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14020397
Abstract: Immunotherapy represents a promising strategy for the treatment of cancer, which functions via the reprogramming and activation of antitumor immunity. However, adverse events resulting from immunotherapy that are related to the low specificity of tumor… read more here.
Keywords: modulation cancer; nanovectors modulation; immunotherapy; landscape nanovectors ... See more keywords