"Chemical modulation of gasdermin-mediated pyroptosis and therapeutic potential".
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DOI: 10.1016/j.jmb.2021.167183
Abstract: Pyroptosis, a lytic form of programmed cell death, both stimulates effective immune responses and causes tissue damage. Gasdermin (GSDM) proteins are a family of pore-forming executors of pyroptosis. While the most-studied member, GSDMD, exerts critical… read more here.
Keywords: modulation gasdermin; biology; mediated pyroptosis; chemical modulation ... See more keywords