Modulation of the innate immune response, antioxidant system and oxidative stress during acute and chronic stress in pacu (Piaractus mesopotamicus).
Sign Up to like & getrecommendations! Published in 2021 at "Fish physiology and biochemistry"
DOI: 10.1007/s10695-021-00940-x
Abstract: Stress is an energy-demanding process, as well as the responses of the innate immune system, that impose a metabolic overload on cellular energy production, which can affect the cellular redox balance, causing oxidative damage. We… read more here.
Keywords: system; stress; innate immune; acute chronic ... See more keywords
Modulation of innate and adaptive immunity by P2X ion channels.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2018.03.026
Abstract: Extracellular ATP is a major component of the inflammatory microenvironment where it accumulates following cell and tissue injury but also as a consequence of non-lytic release from activated inflammatory cells. In the inflammatory microenvironment ATP… read more here.
Keywords: p2x; ion; adaptive immunity; innate adaptive ... See more keywords
Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on their Agonists and Antagonists.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c01049
Abstract: Toll-like receptors (TLRs) are a class of proteins that recognize pathogen-associated molecular patterns (PAMPs) and damaged-associated molecular patterns (DAMPs) and are involved in the regulation of innate immune system. These transmembrane receptors are localized at… read more here.
Keywords: toll like; response; like receptors; innate immune ... See more keywords
Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins
Sign Up to like & getrecommendations! Published in 2018 at "Viruses"
DOI: 10.3390/v10120708
Abstract: Influenza A viruses (IAV) can infect a broad range of animal hosts, including humans. In humans, IAV causes seasonal annual epidemics and occasional pandemics, representing a serious public health and economic problem, which is most… read more here.
Keywords: ns1 proteins; immune responses; host; innate immune ... See more keywords
Modulation of Innate Immune Signaling Pathways by Herpesviruses
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11060572
Abstract: Herpesviruses can be detected by pattern recognition receptors (PRRs), which then activate downstream adaptors, kinases and transcription factors (TFs) to induce the expression of interferons (IFNs) and inflammatory cytokines. IFNs further activate the Janus kinase-signal… read more here.
Keywords: signaling pathways; infection; host innate; immune signaling ... See more keywords