Enantiospecific Positive Allosteric Modulation of α4β2 Nicotinic Receptor Subtypes.
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DOI: 10.1021/acschemneuro.5c00115
Abstract: Nicotinic acetylcholine receptors (nAChRs) are integral to brain function, playing critical roles in cognition and reward pathways. Among these, α4β2 nAChRs are key targets for developing therapeutics to address nicotine addiction and cognitive disorders. Here,… read more here.
Keywords: modulation nicotinic; nicotinic receptor; gat2802; positive allosteric ... See more keywords