Intracellular Receptor Modulation: Novel Approach to Target GPCRs.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2018.03.002
Abstract: Recent crystal structures of multiple G protein-coupled receptors (GPCRs) have revealed a highly conserved intracellular pocket that can be used to modulate these receptors from the inside. This novel intracellular site partially overlaps with the… read more here.
Keywords: intracellular receptor; approach target; novel approach; modulation novel ... See more keywords
Gut Microbiota Modulation as a Novel Therapeutic Strategy in Cardiometabolic Diseases
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DOI: 10.3390/foods11172575
Abstract: The human gut harbors microbial ecology that is in a symbiotic relationship with its host and has a vital function in keeping host homeostasis. Inimical alterations in the composition of gut microbiota, known as gut… read more here.
Keywords: modulation novel; microbiota modulation; cardiometabolic diseases; gut microbiota ... See more keywords