Transglutaminase 2 modulation of NF-κB signaling in astrocytes is independent of its ability to mediate astrocytic viability in ischemic injury
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2017.05.009
Abstract: Transglutaminase 2 (TG2) is a multifunctional protein that can contribute to cell death and cell survival processes in a variety of disease contexts. Within the brain, TG2 has been shown to promote cell death in… read more here.
Keywords: tg2; viability; ability mediate; ischemic injury ... See more keywords
Modulation of NF-kB signaling by mercury compounds in mouse microglia cells and its relationship with glutathione levels
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.275
Abstract: Mercury (Hg) is widely known by its neurotoxicity albeit immunotoxicity occurs at lower exposure levels. Since microglia cells are the major representatives of the immune system in the CNS, we hypothesize Hg compounds disrupt microglia… read more here.
Keywords: mouse microglia; p50 p65; microglia cells; modulation signaling ... See more keywords
Modulation of signaling pathways by DJ-1: An updated overview
Sign Up to like & getrecommendations! Published in 2022 at "Redox Biology"
DOI: 10.1016/j.redox.2022.102283
Abstract: Efforts have been made to understand the physiological and pathological role of DJ-1, a Parkinson’s disease (PD)-associated protein, to provide new insights into PD pathophysiology. Such studies have revealed several neuroprotective roles of DJ-1, from… read more here.
Keywords: pathways updated; signaling pathways; updated overview; modulation ... See more keywords
Modulation of the NF-κB signaling pathway by the HIV-2 envelope glycoprotein and its incomplete BST-2 antagonism.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2017.09.024
Abstract: The HIVs have evolved by selecting means to hijack numerous host cellular factors. HIVs exploit the transcription factor NF-κB to ensure efficient LTR-driven gene transcription. However, NF-κB is primarily known to act as a key… read more here.
Keywords: hiv env; pathway hiv; signaling pathway; bst ... See more keywords
Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation, Autoimmune Diseases, and Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01557
Abstract: Thymic Stromal Lymphopoietin (TSLP) and Interleukin-7 (IL-7) are widely studied cytokines within distinct branches of immunology. On one hand, TSLP is crucially important for mediating type 2 immunity at barrier surfaces and has been linked… read more here.
Keywords: autoimmune diseases; signaling mediated; cancer; tslp ... See more keywords