Allosteric Modulation of Thrombin by Thrombomodulin: Insights from Logistic Regression and Statistical Analysis of Molecular Dynamics Simulations
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DOI: 10.1021/acsomega.4c03375
Abstract: Thrombomodulin (TM), a transmembrane receptor integral to the anticoagulant pathway, governs thrombin’s substrate specificity via interaction with thrombin’s anion-binding exosite I. Despite its established role, the precise mechanisms underlying this regulatory function are yet to… read more here.
Keywords: thrombin; thrombomodulin; thrombin thrombomodulin; modulation thrombin ... See more keywords