Modulation of TLR4 Sialylation Mediated by a Sialidase Neu1 and Impairment of Its Signaling in Leishmania donovani Infected Macrophages
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DOI: 10.3389/fimmu.2019.02360
Abstract: Altered sialylation is generally maintained by a fine balance between sialidases and sialyltransferases, which plays an essential role during disease pathogenesis. TLR4 is a membrane-bound highly sialylated glycoprotein predominantly having α2,3-linked sialic acids. It is… read more here.
Keywords: modulation tlr4; infected macrophages; sialylation; donovani infected ... See more keywords