Modulation of tumor‐associated macrophages in colitis‐associated colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30906
Abstract: Intestinal macrophages are the most abundant immune cells in the small and large intestine, which maintain intestinal homeostasis by clearing invading bacteria and dead cells, secreting anti‐inflammatory cytokines, and inducing tolerance to symbiotic bacteria and… read more here.
Keywords: macrophages colitis; tumor associated; colitis associated; associated macrophages ... See more keywords
Beneficial modulation of the tumor microenvironment and generation of anti-tumor responses by TLR9 agonist lefitolimod alone and in combination with checkpoint inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2019.1659096
Abstract: ABSTRACT Activation of Toll-like receptor 9 (TLR9) is known to foster innate and adaptive immune responses and thus improve immune-mediated control of malignant disease. Lefitolimod is a potent TLR9 agonist without chemical modification developed for… read more here.
Keywords: anti tumor; lefitolimod; tumor microenvironment; tumor ... See more keywords
Metallic Nanoparticles for the Modulation of Tumor Microenvironment; A New Horizon
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.847433
Abstract: Cancer is one of the most critical human challenges which endangers many people’s lives every year with enormous direct and indirect costs worldwide. Unfortunately, despite many advanced treatments used in cancer clinics today, the treatments… read more here.
Keywords: cancer; metallic nanoparticles; modulation tumor; tumor microenvironment ... See more keywords
Therapy-Induced Modulation of the Tumor Microenvironment: New Opportunities for Cancer Therapies
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.582884
Abstract: Advances in immunotherapy have achieved remarkable clinical outcomes in tumors with low curability, but their effects are limited, and increasing evidence has implicated tumoral and non-tumoral components of the tumor microenvironment as critical mediators of… read more here.
Keywords: induced modulation; modulation tumor; cancer; tumor microenvironment ... See more keywords