Articles with "modulator bpam344" as a keyword



The positive allosteric modulator BPAM344 and L‐glutamate introduce an active‐like structure of the ligand‐binding domain of GluK2

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Published in 2024 at "FEBS Letters"

DOI: 10.1002/1873-3468.14824

Abstract: Kainate receptors belong to the family of ionotropic glutamate receptors and contribute to the majority of fast excitatory neurotransmission. Consequently, they also play a role in brain diseases. Therefore, understanding how these receptors can be… read more here.

Keywords: ligand binding; modulator bpam344; binding domain; positive allosteric ... See more keywords