Articles with "modulator glucagon" as a keyword



Photo from wikipedia

Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor.

Sign Up to like & get
recommendations!
Published in 2021 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.1c00029

Abstract: The identification of LSN3318839, a positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R), is described. LSN3318839 increases the potency and efficacy of the weak metabolite GLP-1(9-36)NH2 to become a full agonist at the GLP-1R… read more here.

Keywords: allosteric modulator; glucagon like; glp; modulator glucagon ... See more keywords