Treatment with the Glycosphingolipid Modulator THI Rescues Myelin Integrity in the Striatum of R6/2 HD Mice
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DOI: 10.3390/ijms24065956
Abstract: Huntington’s disease is one of the most common dominantly inherited neurodegenerative disorders caused by an expansion of a polyglutamine (polyQ) stretch in the N-terminal region of huntingtin (Htt). Among all the molecular mechanisms, affected by… read more here.
Keywords: striatum mice; modulator thi; glycosphingolipid modulator; treatment glycosphingolipid ... See more keywords