Articles with "modulators oral" as a keyword



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Polyamidoamine (PAMAM) dendrimers as potential release modulators and oral bioavailability enhancers of vardenafil hydrochloride

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Published in 2019 at "Pharmaceutical Development and Technology"

DOI: 10.1080/10837450.2018.1472611

Abstract: Abstract Vardenafil hydrochloride (VAR) is an erectile dysfunction treating drug. VAR has a short elimination half-life (4–5 h) and suffers low oral bioavailability (15%). This work aimed to explore the dual potential of VAR-dendrimer complexes as… read more here.

Keywords: oral bioavailability; release modulators; bioavailability; vardenafil hydrochloride ... See more keywords