Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model
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DOI: 10.1093/hmg/ddx229
Abstract: TDP-43 is a critical RNA-binding factor associated with RNA metabolism. In the physiological state, maintaining normal TDP-43 protein levels is critical for proper physiological functions of the cells. As such, TDP-43 expression is tightly regulated… read more here.
Keywords: tdp production; drosophila model; production; genetic modulators ... See more keywords