Articles with "modulators treating" as a keyword



Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases.

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Published in 2024 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.4c00178

Abstract: Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer's disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds. read more here.

Keywords: treating neurodegenerative; modulators treating; neurodegenerative diseases; compounds s1p5 ... See more keywords

Natural Bioactive Products as Epigenetic Modulators for Treating Neurodegenerative Disorders

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Published in 2023 at "Pharmaceuticals"

DOI: 10.3390/ph16020216

Abstract: Neurodegenerative disorders (NDDs) are major health issues in Western countries. Despite significant efforts, no effective therapeutics for NDDs exist. Several drugs that target epigenetic mechanisms (epidrugs) have been recently developed for the treatment of NDDs,… read more here.

Keywords: epigenetic modulators; modulators treating; bioactive products; natural bioactive ... See more keywords