SMILE: a novel procedure for subcellular module identification with localisation expansion.
Sign Up to like & getrecommendations! Published in 2018 at "IET systems biology"
DOI: 10.1049/iet-syb.2017.0085
Abstract: Computational clustering methods help identify functional modules in protein-protein interaction (PPI) network, in which proteins participate in the same biological pathways or specific functions. Subcellular localisation is crucial for proteins to implement biological functions and… read more here.
Keywords: novel procedure; subcellular module; localisation; module identification ... See more keywords
Active module identification in intracellular networks using a memetic algorithm with a new binary decoding scheme
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-3495-y
Abstract: BackgroundActive modules are connected regions in biological network which show significant changes in expression over particular conditions. The identification of such modules is important since it may reveal the regulatory and signaling mechanisms that associate… read more here.
Keywords: decoding scheme; active module; module identification; identification ... See more keywords