Identification of gene coexpression modules, hub genes, and pathways related to spinal cord injury using integrated bioinformatics methods
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27908
Abstract: Spinal cord injury (SCI) is characterized by dramatic neurons loss and axonal regeneration suppression. The underlying mechanism associated with SCI‐induced immune suppression is still unclear. Weighted gene coexpression network analysis (WGCNA) is now widely applied… read more here.
Keywords: gene coexpression; hub genes; modules hub; gene ... See more keywords
Identification of Key Modules and Hub Genes of Keloids with Weighted Gene Coexpression Network Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000003014
Abstract: Background: Keloid scarring impairs patients’ quality of life, and although many therapeutic strategies have been developed, most remain unsatisfactory because of limited understanding of the mechanisms underlying keloid development. Methods: A microarray gene expression data… read more here.
Keywords: weighted gene; analysis; hub genes; gene coexpression ... See more keywords
Identification of Key Modules and Hub Genes of Annulus Fibrosus in Intervertebral Disc Degeneration
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DOI: 10.3389/fgene.2020.596174
Abstract: Background: Intervertebral disc degeneration impairs the quality of patients lives. Even though there has been development of many therapeutic strategies, most of them remain unsatisfactory due to the limited understanding of the mechanisms that underlie… read more here.
Keywords: intervertebral disc; hub genes; disc degeneration; modules hub ... See more keywords