Moesin contributes to heat shock gene response through direct binding to the Med15 subunit of the Mediator complex in the nucleus
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DOI: 10.1098/rsob.240110
Abstract: The members of the evolutionary conserved actin-binding Ezrin, Radixin and Moesin (ERM) protein family are involved in numerous key cellular processes in the cytoplasm. In the last decades, ERM proteins, like actin and other cytoskeletal… read more here.
Keywords: moesin; binding; med15; heat shock ... See more keywords
Role of moesin, Src, and ROS in advanced glycation end product‐induced vascular endothelial dysfunction
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DOI: 10.1111/micc.12358
Abstract: The disruption of endothelial integrity and the occurrence of angiogenesis in response to AGEs contribute greatly to micro‐ and macrovascular complications associated with DM. Among human dermal, brain, and retinal vascular ECs, activation of ERM,… read more here.
Keywords: moesin; dysfunction; role moesin; age induced ... See more keywords
Moesin Involvement in Oral Carcinogenesis of the Lower Lip.
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DOI: 10.21873/anticanres.12518
Abstract: BACKGROUND/AIM This study analyzed moesin immunoexpression in 91 lip squamous cell carcinomas and its influence in patients' prognosis. MATERIALS AND METHODS Moesin immunoexpression was evaluated at the invasive tumor front by a semi-quantitative score method.… read more here.
Keywords: moesin involvement; moesin; survival rates; oral carcinogenesis ... See more keywords
Ectopic Endometrial Cell-Derived Exosomal Moesin Induces Eutopic Endometrial Cell Migration, Enhances Angiogenesis and Cytosolic Inflammation in Lesions Contributes to Endometriosis Progression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.824075
Abstract: Background: Endometriosis (EMs) is the most common gynaecological disorder with its etiology and/or pathophysiology remains enigmatic. Recent studies showed that extracellular vesicles (EVs), exosomes in particular, play a critical role in developing various clinical disorders.… read more here.
Keywords: moesin; endometriosis progression; endometrial cell; expression ... See more keywords
A bipartite NLS motif mediates the nuclear import of Drosophila moesin
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DOI: 10.3389/fcell.2024.1206067
Abstract: The ERM protein family, which consists of three closely related proteins in vertebrates, ezrin, radixin, and moesin (ERM), is an ancient and important group of cytoplasmic actin-binding and organizing proteins. With their FERM domain, ERMs… read more here.
Keywords: moesin; motif; nuclear import; bipartite ... See more keywords
Role of Moesin Phosphorylation in Retinal Pericyte Migration and Detachment Induced by Advanced Glycation Endproducts
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DOI: 10.3389/fendo.2020.603450
Abstract: Proliferative diabetic retinopathy (PDR) involves persistent, uncontrolled formation of premature blood vessels with reduced number of pericytes. Our previous work showed that advanced glycation endproducts (AGEs) induced angiogenesis in human umbilical vein endothelial cells, mouse… read more here.
Keywords: moesin; migration; moesin phosphorylation; age bsa ... See more keywords
Bushen Huoxue Attenuates Diabetes-Induced Cognitive Impairment by Improvement of Cerebral Microcirculation: Involvement of RhoA/ROCK/moesin and Src Signaling Pathways
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00527
Abstract: Type 2 Diabetes mellitus (T2DM) is closely correlated with cognitive impairment and neurodegenerative disease. Bushen Huoxue (BSHX) is a compound Chinese medicine used clinically to treat diabetes-induced cognitive impairment. However, its underlying mechanisms remain unclear.… read more here.
Keywords: rhoa; moesin; induced cognitive; cognitive impairment ... See more keywords
[Role of phosphorylated Moesin in the injury of pulmonary microvascular endothelial cells of rats and its mechanism].
Sign Up to like & getrecommendations! Published in 2017 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.issn.2095-4352.2017.09.012
Abstract: OBJECTIVE To investigate the role of phosphorylated Moesin (p-Moesin) in the injury of pulmonary microvascular endothelial cells (PMVECs) of rats induced by tumor necrosis factor-α (TNF-α), and to approach the impact of Rac1 signal pathway… read more here.
Keywords: effect experiment; moesin; expression; rac1 ... See more keywords