Patient Experience of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Qualitative Patient and Clinician Interviews Informing the Development of a Conceptual Model
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DOI: 10.1007/s40120-025-00770-6
Abstract: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare, autoimmune demyelinating central nervous system disease. Currently, little is known about the signs, symptoms, and health-related quality of life (HRQoL) impact of MOGAD from the patient… read more here.
Keywords: disease; mogad; conceptual model; model ... See more keywords
Serum level of IL-1β in patients with inflammatory demyelinating disease: Marked upregulation in the early acute phase of MOG antibody associated disease (MOGAD)
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DOI: 10.1016/j.jneuroim.2020.577361
Abstract: BACKGROUND To evaluate the serum cytokine profiles in patients with myelin oligodendrocyte glycoproteins antibody associated disease (MOGAD), compared to those in neuromyelitis optica spectrum disorder with aquaporin-4 immunoglobulin G (APQ4-IgG+ NMOSD), multiple sclerosis (MS), and other… read more here.
Keywords: apq4 igg; disease; igg nmosd; mogad ... See more keywords
Interleukin-6 inhibition with tocilizumab for relapsing MOG-IgG associated disorder (MOGAD): A case-series and review.
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DOI: 10.1016/j.msard.2020.102696
Abstract: BACKGROUND Myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) associated disorder (MOGAD) is a CNS demyelinating disease distinct from neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis. Some patients with MOGAD exhibit a highly-relapsing and steroid-dependent disease course… read more here.
Keywords: mog igg; disorder; case; mogad ... See more keywords
Towards imaging criteria that best differentiate MS from NMOSD and MOGAD: Large multi-ethnic population and different clinical scenarios.
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DOI: 10.1016/j.msard.2022.103778
Abstract: BACKGROUND The "1/3″ brain magnetic resonance imaging (MRI) criteria including 1) a lesion adjacent to the lateral ventricle and in the inferior temporal lobe, or 2) a juxtacortical lesion, or 3) a Dawson finger-type lesion… read more here.
Keywords: towards imaging; nmosd mogad; imaging criteria; fit lesions ... See more keywords
Seizures and epilepsy in multiple sclerosis, aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder, and myelin oligodendrocyte glycoprotein antibody‐associated disease
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DOI: 10.1111/epi.17315
Abstract: Seizure is one of the manifestations of central nervous system inflammatory demyelinating diseases, which mainly include multiple sclerosis (MS), aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder (AQP4‐NMOSD), and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD). Acute… read more here.
Keywords: mogad; disease; aqp4 nmosd; sclerosis aquaporin ... See more keywords
Interleukin-33 as a biomarker affected intrathecal synthesis of immunoglobulin in NMOSD and MOGAD.
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DOI: 10.1159/000530437
Abstract: INTRODUCTION The purpose of this study was to analyze IL-33 maybe as a biomarker especially with respect to intrathecal immunoglobulin (IgG) synthesis which was involved in the immune -mediated process in the demyelinating disease of… read more here.
Keywords: nmosd mogad; biomarker; mogad; synthesis ... See more keywords
Socioeconomic, Clinical, and Laboratory Parameters Differentiating Pediatric Patients With MOG Antibody–Associated Disease and Multiple Sclerosis
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DOI: 10.1177/08830738231170290
Abstract: Studies indicate differences in the clinical phenotypes and neuroimaging of children with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) compared to multiple sclerosis; however, there are limited data assessing the socioeconomic and paraclinical differences between these… read more here.
Keywords: less likely; associated disease; antibody associated; sclerosis ... See more keywords
Comparison of MRI T2-lesion evolution in pediatric MOGAD, NMOSD, and MS.
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DOI: 10.1177/13524585231166834
Abstract: BACKGROUND Magnetic resonance imaging (MRI) T2-lesions resolve more often in myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) than aquaporin-4 IgG-positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD) and multiple sclerosis (MS) in adults but few… read more here.
Keywords: mogad; brain; lesion; spine ... See more keywords
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) as a novel presentation of CNS autoimmunity in a pediatric patient with Wiskott-Aldrich syndrome (WAS)
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DOI: 10.1212/01.wnl.0000903172.52024.08
Abstract: Objective Report a novel case of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) presenting as relapsing bilateral optic neuritis in a pediatric patient with Wiskott-Aldrich syndrome (WAS). Background WAS is a rare X-linked primary immunodeficiency caused… read more here.
Keywords: glycoprotein antibody; mogad; optic neuritis; oligodendrocyte glycoprotein ... See more keywords
Trans-Synaptic Degeneration in the Visual Pathway in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.
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DOI: 10.1212/wnl.0000000000209156
Abstract: BACKGROUND AND OBJECTIVES We aimed to assess the presence of retinal neurodegeneration independent of optic neuritis (ON) in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and to investigate the development of trans-synaptic anterograde degeneration in these… read more here.
Keywords: glycoprotein antibody; mogad; thickness; visual pathway ... See more keywords
Early Maintenance Treatment Initiation and Relapse Risk Mitigation After a First Event of MOGAD in Adults
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DOI: 10.1212/wnl.0000000000209624
Abstract: Background and Objectives Because myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) is a recently identified autoimmune disorder, the natural history of MOGAD is still not well described. The objective of this study was to describe the… read more here.
Keywords: relapse; relapse risk; treatment; mogad ... See more keywords