Genetic polymorphism of CYP3A4 is associated with poor response to ifosfamide treatment in children with solid embryonic tumors
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DOI: 10.5114/aoms.2019.86648
Abstract: The CYP450 complex participates in the metabolism of ifosfamide, an antineoplastic drug used to treat solid tumors. genes contain several single nucleotide polymorphisms (SNPs) that confer different activity towards the enzyme. The aim of our… read more here.
Keywords: response; median mol; q25 q75; patients genotype ... See more keywords