Fossorial giant Zambian mole-rats have blunted ventilatory responses to environmental hypoxia and hypercapnia.
Sign Up to like & getrecommendations! Published in 2020 at "Comparative biochemistry and physiology. Part A, Molecular & integrative physiology"
DOI: 10.1016/j.cbpa.2020.110672
Abstract: Fossorial giant Zambian mole-rats are believed to live in a hypoxic and hypercapnic subterranean environment but their physiological responses to these challenges are entirely unknown. To investigate this, we exposed awake and freely-behaving animals to… read more here.
Keywords: zambian mole; mole rats; hypercapnia; physiology ... See more keywords
No evidence for multimodal body mass distributions and body mass-related capture order in wild-caught Damaraland mole-rats
Sign Up to like & getrecommendations! Published in 2019 at "Mammalian Biology"
DOI: 10.1016/j.mambio.2018.09.012
Abstract: Division of labour among workers is a universal property of eusocial insect societies. For Damaraland mole-rats (Fukomys damarensis), a eusocial mammal, it was proposed that workers can be divided into morphologically distinct (in terms of… read more here.
Keywords: damaraland mole; mass; capture order; mole rats ... See more keywords
Two major clades of blind mole rats (Nannospalax sp.) revealed by mtDNA and microsatellite genotyping in Western and Central Turkey
Sign Up to like & getrecommendations! Published in 2019 at "Mammalian Biology"
DOI: 10.1016/j.mambio.2018.11.004
Abstract: The Anatolian and the Lesser blind mole rats (Nannospalax xanthodon and N. leucodon) are widely distributed in Anatolia and Thrace and feature remarkable diversity of chromosomal races. The evolutionary relationship among various cytotypes has not… read more here.
Keywords: rats nannospalax; two major; western central; microsatellite genotyping ... See more keywords
Non-invasive assessment of glucocorticoid and androgen metabolite levels in cooperatively breeding Damaraland mole-rats (Fukomys damarensis).
Sign Up to like & getrecommendations! Published in 2018 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2018.05.018
Abstract: Dominant females of cooperative breeding species often use aggression to suppress reproduction of subordinate females, resulting in subordinates experiencing stress-related increases in glucocorticoid levels, which may cause reproductive down-regulation. This would suggest a general pattern… read more here.
Keywords: damaraland mole; mole rats; cooperatively breeding; androgen ... See more keywords
Sociality does not drive the evolution of large brains in eusocial African mole-rats
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-26062-8
Abstract: The social brain hypothesis (SBH) posits that the demands imposed on individuals by living in cohesive social groups exert a selection pressure favouring the evolution of large brains and complex cognitive abilities. Using volumetry and… read more here.
Keywords: mole rats; african mole; evolution large; large brains ... See more keywords
Hematologic adaptation to the subterranean environment by the naked mole-rat, Heterocephalus glaber (Ctenohystrica: Heterocephalidae)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Mammalogy"
DOI: 10.1093/jmammal/gyaa053
Abstract: One method burrowing animals are hypothesized to use in adapting to the presumed hypoxic subterranean environment is increasing the oxygen-carrying capacity of blood. A number of recent studies have examined hematologic parameters in laboratory-reared naked… read more here.
Keywords: mole rats; chemistry; naked mole; subterranean environment ... See more keywords
Growth affects dispersal success in social mole-rats, but not the duration of philopatry
Sign Up to like & getrecommendations! Published in 2018 at "Biology Letters"
DOI: 10.1098/rsbl.2018.0005
Abstract: In naked mole-rats (Heterocephalus glaber), some non-breeding males show faster growth and are more likely to disperse than others. These differences have been suggested to be the result of a specialized developmental strategy leading to… read more here.
Keywords: growing males; mole rats; dispersal success; philopatry ... See more keywords
Auditory brainstem development of naked mole-rats (Heterocephalus glaber)
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2022.0878
Abstract: Life underground often leads to animals having specialized auditory systems to accommodate the constraints of acoustic transmission in tunnels. Despite living underground, naked mole-rats use a highly vocal communication system, implying that they rely on… read more here.
Keywords: mole rats; naked mole; development; auditory brainstem ... See more keywords
Ventilatory responses to hypoxic and hypercapnic environments in naked mole‐rats
Sign Up to like & getrecommendations! Published in 2023 at "Acta Physiologica"
DOI: 10.1111/apha.13963
Abstract: Extreme environments are powerful drivers of physiological adaptation. Naked mole‐rats offer an informative example of this relationship as they putatively encounter intermittent hypoxia and hypercapnia in their subterranean habitat. This has presumably driven the evolution… read more here.
Keywords: ventilatory responses; naked mole; mole rats; hypoxia hypercapnia ... See more keywords
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
Sign Up to like & getrecommendations! Published in 2025 at "Science"
DOI: 10.1126/science.adp5056
Abstract: Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that naked mole-rat cyclic guanosine monophosphate-adenosine monophosphate… read more here.
Keywords: cgas; naked mole; mole rats; repair ... See more keywords
Programmed aging of mammals: Proof of concept and prospects of biochemical approaches for anti-aging therapy
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry (Moscow)"
DOI: 10.1134/s000629791712001x
Abstract: Abstract(i) In 2015-2017 we compared possible reasons for longevity of two mammalian highly social species, i.e. naked mole rats and humans. We proposed that in both cases longevity is a result of neoteny, prolongation of… read more here.
Keywords: mole rats; phenoptosis; program; naked mole ... See more keywords