Prospective Evaluation of Molecular Assays for Diagnosis of Vaginitis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01264-19
Abstract: Molecular tests to diagnose conditions involving the disruption of normal microbiota are difficult to optimize. Using Nugent-scored Gram stain (NS) as the reference standard, we evaluated the performance of 3 molecular assays for the diagnosis… read more here.
Keywords: reference standard; vaginitis; affirm; assays diagnosis ... See more keywords
P823 Comparison of copan urispongetm to colli-pee for the collection of urine for HPV detection with molecular assays
Sign Up to like & getrecommendations! Published in 2019 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2019-sti.868
Abstract: Background Urine specimen collection is non-invasive and better accepted by patients for HPV and STI screening. The Copan UriSpongeTM, a Liquid Based Microbiology device, used for urine collection for culture and molecular assays. It consists… read more here.
Keywords: copan urispongetm; detection; molecular assays; colli ... See more keywords
Development and Validation of Molecular Assays for Limited Tissue Samples
Sign Up to like & getrecommendations! Published in 2019 at "Acta Cytologica"
DOI: 10.1159/000499109
Abstract: As the value of molecular testing of cancer specimens increases, the number of tests imposed on tumor specimens also increases, often in tension with the amount of tumor material available. To develop and validate molecular… read more here.
Keywords: development validation; molecular assays; assays limited; validation molecular ... See more keywords
Resolving the hematopoietic stem cell state by linking functional and molecular assays.
Sign Up to like & getrecommendations! Published in 2023 at "Blood"
DOI: 10.1182/blood.2022017864
Abstract: One of the most challenging aspects of stem cell research is the reliance on retrospective assays for ascribing function. This is especially problematic for hematopoietic stem cell (HSC) research where the current functional assay that… read more here.
Keywords: cell; state; stem cell; molecular assays ... See more keywords
Molecular assessment of mycobacterial burden in the treatment of nontuberculous mycobacterial disease
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DOI: 10.1183/23120541.00435-2022
Abstract: Introduction Nontuberculous pulmonary disease causes significant morbidity and mortality. Efforts to tackle infections are hampered by the lack of reliable biomarkers for diagnosis, assessment and prognostication. The aim of this study was to develop molecular… read more here.
Keywords: disease; nontuberculous mycobacterial; molecular assays; assays developed ... See more keywords
Diagnostic performance of molecular and serological tests of SARS-CoV-2 on well-characterised specimens from COVID-19 individuals: The EDCTP "PERFECT-study" protocol (RIA2020EF-3000)
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273818
Abstract: Background The SARS-CoV-2 pandemic is a global threat affecting 210 countries, with 2,177,469 confirmed cases and 6.67% case fatality rate as of April 16, 2020. In Africa, 17,243 cases have been confirmed, but many remain… read more here.
Keywords: well characterised; performance; molecular assays; care ... See more keywords
Geographical Variability Affects CCHFV Detection by RT–PCR: A Tool for In-Silico Evaluation of Molecular Assays
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11100953
Abstract: The Crimean–Congo hemorrhagic fever virus (CCHFV) is considered to be a major emerging infectious threat, according to the WHO R&D blueprint. A wide range of CCHFV molecular assays have been developed, employing varied primer/probe combinations.… read more here.
Keywords: molecular assays; cchfv; variability; cchfv detection ... See more keywords
Performance of 2 Polymerization Protocols Targeting Cloned Toxoplasma Parasites
Sign Up to like & getrecommendations! Published in 2018 at "Open Access Macedonian Journal of Medical Sciences"
DOI: 10.3889/oamjms.2018.400
Abstract: BACKGROUND: Toxoplasma gondii is a common parasitic infection of humans. Infection is usually mild. Serious complications can occur in pregnant and immunocompromised patients. AIM: The present study aims to investigate the performance of 2 different… read more here.
Keywords: polymerization protocols; performance polymerization; molecular assays; protocols targeting ... See more keywords