Creating a ‘Molecular Band-Aid’; Blocking an Exposed Protease Target Site in Desmoplakin
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DOI: 10.3390/jpm11050401
Abstract: Desmoplakin (DSP) is a large (~260 kDa) protein found in the desmosome, a subcellular complex that links the cytoskeleton of one cell to its neighbor. A mutation ‘hot-spot’ within the NH2-terminal third of the DSP… read more here.
Keywords: dsp; band aid; molecular band; target site ... See more keywords