Arrayed Molecular Barcoding of Leukemic Stem Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0810-4_21
Abstract: Functional screens on cancer cells using compound or protein libraries are usually performed in vitro. However, to assess the effects on leukemia stem cells (LSCs) in a screening setting, methodologies that allow for a high-throughput… read more here.
Keywords: leukemia cells; molecular barcoding; stem cells; arrayed molecular ... See more keywords
Abstract 5690: Optimized molecular barcoding enables accurate targeted mutation detection in circulating cell-free DNA (cfDNA)
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5690
Abstract: The evaluation of cfDNA allows novel approaches to noninvasive detection of actionable alterations, resistance mechanisms, and tumor monitoring in patients with cancer. Importantly, tumor-specific DNA fragments represent a small minority of the cfDNA and can… read more here.
Keywords: detection; dna; cfdna; molecular barcoding ... See more keywords
Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing.
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DOI: 10.1261/rna.063925.117
Abstract: Genome editing has proven to be highly potent in the generation of functional gene knockouts in dividing cells. In the CNS however, efficient technologies to repair sequences are yet to materialize. Reprogramming on the mRNA… read more here.
Keywords: viral vectors; vectors enables; enables mapping; barcoding viral ... See more keywords
Single-Cell Molecular Barcoding to Decode Multimodal Information Defining Cell States
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DOI: 10.14348/molcells.2023.2168
Abstract: Single-cell research has provided a breakthrough in biology to understand heterogeneous cell groups, such as tissues and organs, in development and disease. Molecular barcoding and subsequent sequencing technology insert a single-cell barcode into isolated single… read more here.
Keywords: multimodal information; cell; single cell; molecular barcoding ... See more keywords